Dan is a Postdoctoral Associate in Dr. Guangping Gao’s laboratory at the Horae Gene Therapy Center, University of Massachusetts Medical School. He received B.S. in life sciences from Fudan University in 2006, and Ph.D. in genetics and genomic sciences from the University of Alabama at Birmingham (UAB) in 2012. He performed his graduate work in Dr. David Bedwell’s laboratory at UAB, where he focused on developing nonsense suppression therapy to treat a lysosomal storage disorder caused by nonsense mutations, and successfully demonstrated the therapeutic efficacy in a mouse model of the disease. Since he joined Dr. Gao’s lab in 2012, he has been focusing on recombinant adeno-associated virus (rAAV)-mediated gene therapy. His research area includes rAAV vector development, rAAV capsid engineering, central nervous system (CNS) gene delivery and gene therapy, therapeutic gene editing, and animal modeling of human diseases in mice and non-human primates.
