Kévin Contrepois is an expert in metabolite profiling and liquid chromatography tandem mass spectrometry. He leads the metabolomics and lipidomics research in the Snyder laboratory at Stanford University, California, USA. By integrating multi-omics data sets, he is interested in the discovery of biomarkers and in understanding the pathogenesis of common diseases (i.e. cancer, diabetes, and cardiovascular disorders), with a special emphasis on host-gut microbiome interactions. He recently developed an optimized analytical platform involving the combination of HILIC- and RPLC-MS for the comprehensive metabolic profiling of human urine and plasma.
He received his Ph.D. from the University of Paris-Sud (France) where under the supervision of Carl Mann and François Fenaille, his doctoral research focused on identifying chromatin modifications associated with cellular senescence and understanding their biological implications. He developed an UHPLC-MS methodology on intact proteins to characterize and quantify histone variants and post-translational modifications in a high-throughput manner.
